mLiver Cancer RoadMap – Say YES to HOPE

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Home
About Us
Advanced Cancer
- Cancer Type
  - Bladder
  - Brain
  - Breast
  - Cervical
  - Colorectal
  - Esophageal
  - GIST
  - Liver
  - Lung
  - Melanoma
  - Neuroendocrine
  - Ovarian
  - Pancreatic
  - Prostate
  - Renal Cell
- If Cancer Spreads
Support

Metastatic Liver Cancer (Hepatocellular Carcinoma) Roadmap

Understanding your diagnosis, liver health, tumor biology, and treatment history can help guide conversations with your care team and help you explore available options.

1. Diagnosis & Liver Health History

What type of liver cancer were you diagnosed with? When was advanced or metastatic disease diagnosed? Do you have underlying liver disease?

Cirrhosis Hepatitis B Hepatitis C Fatty liver disease (NAFLD / NASH) Alcohol-related liver disease No known liver disease Not sure

2. Liver Function & Lab Tests

Have doctors discussed liver function testing?

Liver function tests may include:

Bilirubin AST ALT Alkaline phosphatase Albumin INR / Prothrombin time Platelet count Creatinine Not sure

These tests help doctors evaluate liver function and guide treatment decisions.

3. Liver Function Classification

Has your care team discussed liver function classification?

Child-Pugh Class MELD Score

4. BCLC Staging

Has your care team discussed BCLC stage?

5. Tumor Characteristics

How many liver tumors are present? Size of largest tumor Has the tumor grown into blood vessels?

6. Transplant Eligibility

Has liver transplant been discussed?

Have doctors mentioned transplant criteria?

Milan Criteria UCSF Criteria Other transplant criteria Not sure

7. Tumor Biomarkers

Has your tumor been tested for any of the following?

AFP (alpha-fetoprotein) AFP-L3 DCP / PIVKA-II PD-L1 expression MSI-High / mismatch repair deficiency Tumor mutational burden NTRK gene fusion FGFR mutation TERT mutation CTNNB1 mutation Other genomic mutation No mutations identified Not sure

8. Where Has the Cancer Spread?

Select all areas identified.

Liver only Lymph nodes Lung Bone Peritoneum Adrenal glands Brain Other organs Not sure

Lung Metastases

How many lung tumors are present?

Bone Metastases

How many bone sites are involved?

Brain Metastases

Has cancer spread to the brain? Treatments discussed?

Surgery Stereotactic radiosurgery Whole brain radiation Medication treatment only Not sure

9. Liver Complications

Have doctors discussed liver-related complications?

Ascites (fluid buildup in abdomen) Hepatic encephalopathy Varices or bleeding risk Jaundice Portal hypertension Not sure

If ascites is present, how severe is it? Ascites management may include:

Diuretics Paracentesis Salt restriction TIPS procedure Not sure

10. Treatment Goals & Planning

What has your care team described as the primary goal of treatment? How will doctors evaluate whether treatment is working?

CT scans MRI scans PET scans AFP blood tests Symptom improvement Not sure

How often are scans planned?

11. Prior Systemic Treatments

Immunotherapy combinations

Atezolizumab + Bevacizumab Durvalumab + Tremelimumab Other combination therapy Not sure

Immunotherapy

Pembrolizumab Nivolumab Other immunotherapy Not sure

Targeted therapy

Sorafenib Lenvatinib Regorafenib Cabozantinib Ramucirumab Other targeted therapy Not sure

Clinical trials Current treatment

Immunotherapy Targeted therapy Combination therapy Clinical trial Not currently receiving treatment Not sure

12. Prior Liver-Directed Treatments

Surgery

Liver tumor removal Liver transplant Surgery for metastatic tumors No surgery

Embolization therapies

TACE Y-90 radioembolization TAE (bland embolization) Hepatic artery infusion therapy Portal vein embolization Not sure

Ablation

Radiofrequency ablation Microwave ablation Cryoablation Not sure

Radiation

SBRT Proton radiation Other radiation therapy None

13. Your Health, Priorities & Questions

How are you feeling in daily life? Symptoms you would like help managing

Abdominal pain Fatigue Weight loss Loss of appetite Ascites Other symptoms None currently

What matters most to you right now? Notes for your care team My Questions for My Care Team

About You (Optional)

You can skip this section. It helps us understand who is using this tool in aggregate.

Age Range Race / Ethnicity

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Cancer Roadmap

Physician Discussion Summary

For Informational Purposes Only – Not Medical Advice

The information provided by this tool is intended for educational and informational purposes only. This tool does not provide medical advice, professional diagnosis, opinion, or treatment to you or any other individual.

Consult Your Physician: This information is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.
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